Thursday, November 29, 2018

Neanderthal populations from different Caucasus regions had strong social connections



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IMAGE: A - obsidian in rocks formed during the eruption; B, C - obsidian boulders ( "bombs "), differing in color and shape. view more 
Credit: Ekaterina V. Doronicheva et al. / Journal of Archaeological Science: Reports 2018
Research group from Russia and the United States analyzed samples of obsidian volcanic glass in Kabardino-Balkaria. It turned out that more than 70 thousand years ago, Neanderthals transferred this mineral to distances up to 250 kilometers and used it to manufacture tools. These findings help to understand how populations from different regions communicated in antiquity. The study was supported by the Russian Science Foundation and is published in the Journal of Archaeological Science: Reports.

When volcanoes erupted, the ejected lava hardens formed a mixture of various minerals, including obsidian. In the Stone Age, the ancient people used this material extensively to create tools. In fact, we use it even now: in surgery, for the manufacture of dark glass and jewelry. The elemental composition of obsidian is unique not only for each volcano, but also for each eruption. This makes it possible to determine precisely the specific archaeological site, where particular obsidian sample originated from.

According to earlier studies, in the Paleolithic in Central Europe and the Caucasus, obsidians were actively transferred from one settlement to another, and over time the distance of its transportation increased from 100 to more than 700 kilometers.

Scientists from the non-profit organization "Laboratory of Prehistory" analyzed the elemental composition of obsidian samples from various Neanderthals ites of the Central and North-Western Caucasus, which were found during several expeditions. The obsidian composition turned out to be almost identical for many tools, which indicates their common origin. New data also indicates that obsidian was transported over more than 250 kilometers from sources in the Central Caucasus to the North-West Caucasus during the Middle Paleolithic. At the same time, new studies show that the Central Caucasus populations cultural tradition differed from the Neanderthals of the North-West Caucasus. So archaeologists have yet to figure out how the interaction between these different Neanderthals groups was build in this period.

Scientists also found that in the Upper Paleolithic, people transported obsidians from the Elbrus region and the South Caucasus to the Mezmay cave, which is located in the North-West Caucasus. The length of migration was 250 and 450 kilometers respectively. The researchers suggest that in the Upper Paleolithic there was already a developed social network between groups of people from different regions.

"The study of cultural areas, the impact of innovations and mechanisms for the dissemination of new technologies is one of the most important tasks of modern research. Our work reliably shows the existence of connections of the population of different regions in antiquity. These results can be widely used in university lectures, as well as in modern textbooks for middle and high school. Also, the results of recent studies can be used in the design of expositions of museums and thematic exhibitions," summarizes Ekaterina Doronicheva, one of the authors of the work, Ph.D., research associate of the "Laboratory of Prehistory".

Wednesday, November 28, 2018

First ancient DNA from mainland Finland reveals origins of Siberian ancestry in region

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Researchers from the Max-Planck-Institute for the Science of Human History and the University of Helsinki have analyzed the first ancient DNA from mainland Finland. As described in Nature Communications, ancient DNA was extracted from bones and teeth from a 3,500 year-old burial on the Kola Peninsula, Russia, and a 1,500 year-old water burial in Finland. The results reveal the possible path along which ancient people from Siberia spread to Finland and Northwestern Russia.

Researchers found the earliest evidence of Siberian ancestry in Fennoscandia in a population inhabiting the Kola Peninsula, in Northwestern Russia, dating to around 4,000 years ago. This genetic ancestry then later spread to populations living in Finland. The study also found that people genetically similar to present-day Saami people inhabited areas in much more southern parts of Finland than the Saami today.

For the present study, genome-wide genetic data from 11 individuals were retrieved. Eight individuals came from the Kola Peninsula, six from a burial dated to 3,500 years ago, and two from an 18th to 19th century Saami cemetery. "We were surprised to find that the oldest samples studied here had the highest proportion of Siberian ancestry," says Stephan Schiffels, co-senior author of the study, of the Max Planck Institute for the Science of Human History.

The other three individuals analyzed for the study came from a water burial in Levänluhta, Finland. Levänluhta is one of the oldest known burials in Finland in which human bones have been preserved. The bodies were buried in what used to be a small lake or a pond, and this seems to have contributed to exceptionally good preservation of the remains.

Siberian ancestry persists today

The study compared the ancient individuals not only to each other, but also to modern populations, including Saami, Finnish and other Uralic language speakers. Among modern European populations, the Saami have the largest proportion of this ancient Siberian ancestry. Worldwide, the Nganasan people, from north Siberia, have the largest proportion of ancient Siberian ancestry.

"Our results show that there was a strong genetic connection between ancient Finnish and ancient Siberian populations," says Thiseas Lamnidis, co-first author of the study, "suggesting that ancient populations from Siberia may have also shared a subsistence strategy, languages and/or cultural behaviours with Bronze Age and Iron Age Finns, despite the large geographical distance." Ancient Finnish populations possibly lived a mobile, nomadic life, trading and moving over a large range, with far-reaching contacts to other populations.

People found in Levänluhta, Finland, most resemble modern-day Saami

The researchers found that the population in Levänluhta was more closely related to modern-day Saami people than to the non-Saami Finnish population today.

"People closely related to the Saami inhabited much more southern regions of Finland than the Saami do today," explains Kerttu Majander, co-first author, of the University of Helsinki and the Max Planck Institute for the Science of Human History. Interestingly, a recent linguistic study suggested that the place names around Levänluhta trace back to Saami languages.

"This is the first exploration of ancient DNA from Finland and the results are very interesting," states Schiffels. "However more ancient DNA studies from the area will be necessary to better understand whether the patterns we've seen are representative of Finland as a whole."

The study was conducted as a collaboration between the SUGRIGE-project (Universities of Helsinki and Turku), and the Max Planck Institute for the Science of Human History. The archaeological materials and expertise were provided by the Peter the Great Museum of Anthropology and Ethnography (Kunstkamera) and the Levänluhta-project with the Finnish Heritage Agency.

As far back as 40,000 years ago, humans kept track of time using relatively sophisticated knowledge of the star,



 
Some of the world's oldest cave paintings have revealed how ancient people had relatively advanced knowledge of astronomy. Animal symbols represent star constellations in the night sky, and are used to mark dates and events such as comet strikes, analysis from the University of Edinburgh suggests.
Credit: Alistair Coombs
Some of the world's oldest cave paintings have revealed how ancient people had relatively advanced knowledge of astronomy.

The artworks, at sites across Europe, are not simply depictions of wild animals, as was previously thought. Instead, the animal symbols represent star constellations in the night sky, and are used to represent dates and mark events such as comet strikes, analysis suggests.

They reveal that, perhaps as far back as 40,000 years ago, humans kept track of time using knowledge of how the position of the stars slowly changes over thousands of years.

The findings suggest that ancient people understood an effect caused by the gradual shift of Earth's rotational axis. Discovery of this phenomenon, called precession of the equinoxes, was previously credited to the ancient Greeks.

Around the time that Neanderthals became extinct, and perhaps before humankind settled in Western Europe, people could define dates to within 250 years, the study shows.

The findings indicate that the astronomical insights of ancient people were far greater than previously believed. Their knowledge may have aided navigation of the open seas, with implications for our understanding of prehistoric human migration.

Researchers from the Universities of Edinburgh and Kent studied details of Palaeolithic and Neolithic art featuring animal symbols at sites in Turkey, Spain, France and Germany.

They found all the sites used the same method of date-keeping based on sophisticated astronomy, even though the art was separated in time by tens of thousands of years.

Researchers clarified earlier findings from a study of stone carvings at one of these sites -- Gobekli Tepe in modern-day Turkey -- which is interpreted as a memorial to a devastating comet strike around 11,000 BC. This strike was thought to have initiated a mini ice-age known as the Younger Dryas period.

They also decoded what is probably the best known ancient artwork -- the Lascaux Shaft Scene in France. The work, which features a dying man and several animals, may commemorate another comet strike around 15,200 BC, researchers suggest.

The team confirmed their findings by comparing the age of many examples of cave art -- known from chemically dating the paints used -- with the positions of stars in ancient times as predicted by sophisticated software.

The world's oldest sculpture, the Lion-Man of Hohlenstein-Stadel Cave, from 38,000 BC, was also found to conform to this ancient time-keeping system.

This study was published in Athens Journal of History.

Dr Martin Sweatman, of the University of Edinburgh's School of Engineering, who led the study, said: "Early cave art shows that people had advanced knowledge of the night sky within the last ice age. Intellectually, they were hardly any different to us today.

"These findings support a theory of multiple comet impacts over the course of human development, and will probably revolutionise how prehistoric populations are seen."

Monday, November 19, 2018

The 'Swiss Army knife of prehistoric tools' found in Asia



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IMAGE: These artifacts found in China are among the nearly four dozen that reflect the Levallois technique of toolmaking. In a paper published Nov. 19 in Nature, researchers date these artifacts... view more 
Credit: Marwick et al.
New analysis of artifacts found at a South China archaeological site shows that sophisticated tool technology emerged in East Asia earlier than previously thought.

A study by an international team of researchers, including from the University of Washington, determines that carved stone tools, also known as Levallois cores, were used in Asia 80,000 to 170,000 years ago. Developed in Africa and Western Europe as far back as 300,000 years ago, the cores are a sign of more-advanced toolmaking -- the "multi-tool" of the prehistoric world -- but, until now, were not believed to have emerged in East Asia until 30,000 to 40,000 years ago.

With the find -- and absent human fossils linking the tools to migrating populations -- researchers believe people in Asia developed the technology independently, evidence of similar sets of skills evolving throughout different parts of the ancient world.

The study is published online Nov. 19 in Nature.

"It used to be thought that Levallois cores came to China relatively recently with modern humans," said Ben Marwick, UW associate professor of anthropology and one of the paper's corresponding authors. "Our work reveals the complexity and adaptability of people there that is equivalent to elsewhere in the world. It shows the diversity of the human experience."

Levallois-shaped cores -- the "Swiss Army knife of prehistoric tools," Marwick said -- were efficient and durable, indispensable to a hunter-gatherer society in which a broken spear point could mean certain death at the claws or jaws of a predator. The cores were named for the Levallois-Perret suburb of Paris, where stone flakes were found in the 1800s.

Featuring a distinctive faceted surface, created through a sequence of steps, Levallois flakes were versatile "blanks," used to spear, slice, scrape or dig. The knapping process represents a more sophisticated approach to tool manufacturing than the simpler, oval-shaped stones of earlier periods.

The Levallois artifacts examined in this study were excavated from Guanyindong Cave in Guizhou Province in the 1960s and 1970s. Previous research using uranium-series dating estimated a wide age range of the archaeological site -- between 50,000 and 240,000 years old -- but that earlier technique focused on fossils found away from the stone artifacts, Marwick said. Analyzing the sediments surrounding the artifacts provides more specific clues as to when the artifacts would have been in use.

Marwick and other members of the team, from universities in China and Australia, used optically stimulated luminescence (OSL) to date the artifacts. OSL can establish age by determining when a sediment sample, down to a grain of sand, was last exposed to sunlight -- and thus, how long an artifact may have been buried in layers of sediment.

"Dating for this site was challenging because it had been excavated 40 years ago, and the sediment profile was exposed to air and without protection. So trees, plants, animals, insects could disturb the stratigraphy, which may affect the dating results if conventional methods were used for dating," said Bo Li , an associate professor of archaeology at the University of Wollongong in Australia and one of the paper's corresponding authors. "To solve this problem we used a new single-grain dating technique recently developed in our OSL lab at the University of Wollongong to date individual mineral grains in the sediment. Luckily we found residual sediment left over by the previous excavations, so that allowed us to take samples for dating."

The researchers analyzed more than 2,200 artifacts found at Guanyindong Cave, narrowing down the number of Levallois-style stone cores and flakes to 45. Among those believed to be in the older age range, about 130,000 to 180,000 years old, the team also was able to identify the environment in which the tools were used: an open woodland on a rocky landscape, in "a reduced rainforest area compared to today," the authors note.

In Africa and Europe these kinds of stone tools are often found at archaeological sites starting from 300,000 and 200,000 years ago. They are known as Mode III technology, part of a broad evolutionary sequence that was preceded by hand-axe technology (Mode II) and followed by blade tool technology (Mode IV).

Archaeologists thought that Mode IV technologies arrived in China by migration from the West, but these new finds suggest they could have been locally invented. At the time people were making tools in Guanyindong Cave, the Denisovans -- ancestors to Homo sapiens and relative contemporaries to Neandertals elsewhere in the world -- roamed East Asia. But while hundreds of fossils of archaic humans and related artifacts, dating as far back as more than 3 million years ago, have been found in Africa and Europe, the archaeological record in East Asia is sparser.

That's partly why a stereotype exists, that ancient peoples in the region were behind in terms of technological development, Marwick said.

"Our work shows that ancient people there were just as capable of innovation as anywhere else. Technological innovations in East Asia can be homegrown, and don't always walk in from the West," he said.

The independent emergence of the Levallois technique at different times and places in the world is not unique in terms of prehistoric innovations. Pyramid construction, for one, appeared in at least three separate societies: the Egyptians, the Aztecs and the Mayans. Boatbuilding began specific to geography and reliant on a community's available materials. And writing, of course, developed in various forms with distinct alphabets and characters.

In the evolution of tools, Levallois cores represent something of a middle stage. Subsequent manufacturing processes yielded more-refined blades made of rocks and minerals that were more resistant to flaking, and composites that, for example, combined a spear point with blades along the edge. The appearance of blades later in time indicates a further increase in the complexity and the number of steps required to make the tools.

"The appearance of the Levallois strategy represents a big increase in the complexity of technology because there are so many steps that have to work in order to get the final product, compared to previous technologies," Marwick said.

Thursday, November 15, 2018

New virtual reconstruction of a Neanderthal thorax suggests another breathing mechanism


The results show significant morphological differences pointing to a respiratory mechanism that was different compared with that of modern humans
University of the Basque Country
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IMAGE: This is an image of the reconstruction of the thorax of Kebara 2. Scale = 5 cm. view more 
Credit: A. Gómez-Olivencia, A. Barash and E. Been
Neanderthals were hunter-gatherers who inhabited western Eurasia for more than 200 thousand years during glacial as well as interglacial periods until they became extinct around 40 thousand years ago. While some of the anatomical regions of these extinct humans are well known, others, such as the vertebral column and the ribs, are less well known because these elements are more fragile and not well preserved in the fossil record. In 1983 a partial Neanderthal skeleton (known officially as Kebara 2, and nicknamed "Moshe") belonging to a young male Neanderthal individual who died some 60,000 years ago was found in the Kebara site (Mount Carmel, Israel). While this skeleton does not preserve the cranium because some time after burial the cranium was removed, probably as a consequence of a funerary ritual. However, all the vertebrae and ribs are preserved, and so are other fragile anatomical regions, such as the pelvis or the hyoid bone (a bone in the neck to which some of the tongue muscles are attached). So it is the skeleton that preserves the most complete thorax in the fossil record.
New statistical and virtual reconstruction methods have enabled the researchers to extract new information, which has just been published in the prestigious journal Nature Communications.
For over 150 years, Neanderthal remains have been found at many sites in Europe and Western Asia (including the Middle East), and the thorax morphology of this human species has been a subject of debate since 1856, when the first ribs belonging to this human group were found. Over the past decade, virtual reconstructions have become a new tool that is increasingly being used in fossil study. This methodology is particularly useful with fragile fossils, such as the vertebra and ribs that form the thorax. Nearly two years ago, the same research team created a reconstruction of the spine of this Neanderthal individual; it displays the preserved spine of Kebara 2 showing less pronounced curves in these humans when compared with Homo sapiens. The team's paper, published in the book "Human Paleontology and Prehistory," pointed to a straighter spine than that of modern humans.
For this virtual model of the thorax, researchers used both direct observations of the Kebara 2 skeleton, currently housed at Tel Aviv University, and medical CT (computerized axial tomography) scans of the vertebrae, ribs and pelvic bones. Once all the anatomical elements had been assembled, the virtual reconstruction was done by means of 3D software specifically designed for this purpose. "This was meticulous work," said Alon Barash of Bar Ilan University in Israel. "We had to scan each vertebra and all of the rib fragments individually and then reassemble them in virtual 3D."
"In the reconstruction process, it was necessary to virtually 'cut' and realign some of the parts that displayed deformation, and mirror-image the ribs that had been best preserved in order to substitute the poorly preserved ones on the other side," said Asier Gómez-Olivencia, an Ikerbasque research fellow at the University of the Basque Country.
"The differences between the thorax of a Neanderthal and of a modern human are striking," said Daniel García-Martínez and Markus Bastir, researchers at the National Museum of Natural Sciences (MNCN-CSIC) and co-authors of the work. "The Neanderthal spine is located more inside the thorax with respect to the ribs, which provides more stability. The thorax is also wider in its lower part," added Mikel Arlegi (UPV/EHU).
"The wider lower thorax of Neanderthals and the more horizontal orientation of the ribs, as shown in its reconstruction, suggest that Neanderthals relied more on the diaphragm for breathing," said Ella Been of the Ono Academic College. "Modern humans rely on both the diaphragm and on the expansion of the rib cage. Here we can see how new technologies and methodologies in the study of fossil remains are providing new information to understand extinct species."
This new information is consistent with the recent works on the larger lung capacity of Neanderthals published by two of the co-authors of this study, Markus Bastir and Daniel García-Martínez (Virtual Anthropology Laboratory of the MNCN), in which they support the presence of greater lung capacity in the Neanderthals.).
Patricia Kramer of the University of Washington sums it all up thus: "This is the culmination of 15 years of research into the Neanderthal thorax; we hope that future genetic analyses will provide additional clues about the respiratory physiology of the Neanderthals".

Ashkenazi Jewish founder mutation identified for Leigh Syndrome



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IMAGE: Chuckie Barnett at age 3 (left) and Michael Barnett at age 5. view more 
Credit: Marsha Barnett
Over 30 years ago, Marsha and Allen Barnett lost their sons to a puzzling childhood disease that relentlessly attacked their nervous systems and sapped their energy. After five-year-old Chuckie died suddenly in 1981, doctors provided a name for the disease: Leigh syndrome. Leigh syndrome is a complex disorder typically caused by dysfunctional mitochondria, the tiny batteries inside all cells that generate our energy. Two years later, the same disease killed Michael, Chuckie's older brother, when he was 10 years old.
Earlier this year, Mrs. Barnett, who lives in southeastern Pennsylvania, received a phone call from a physician she knew, Marni J. Falk, MD, at Children's Hospital of Philadelphia (CHOP), where Barnett has long supported research in mitochondrial medicine. "She asked about Chuckie's and Michael's symptoms, then told me, 'I think we found the causal gene mutation,'" she said.
Falk, the Executive Director of CHOP's Mitochondrial Medicine Frontier Program, led a research team that identified the inherited mutation in the Barnett family, a change in one nuclear gene that arose spontaneously generations ago among both parents' Ashkenazi Jewish ancestors. Scores of different genes harbor mutations that may cause Leigh syndrome, by many different possible inheritance patterns. The mutation in this family was present on both copies of the same gene in both affected brothers, and was also seen in two other children in the study with Leigh syndrome who were not related to them.
The study team, a research collaboration involving multiple centers to prove that the gene mutation definitely impaired mitochondrial function, published its findings in the October 2018 issue of Human Molecular Genetics. Falk's co-study leader was Michio Hirano, MD, of Columbia University, and the study's co-first authors were Rebecca D. Ganetzky, MD, of CHOP, and Emanuele Barca, PhD, of Columbia University.
Leigh syndrome, named after a British neuropsychologist who first described it in 1951, involves metabolic strokes deep in the brain, with a loss of skills from stressors such as fever, illness and anesthesia. It has historically had a high mortality rate in childhood or adolescence. Over 90 different genes necessary for mitochondria to function properly are now known to cause it, with disease-causing gene variants rooted in DNA, either within a cell's nucleus or in the separate mitochondrial genome.
Impaired cellular energy production in Leigh syndrome causes patients to experience progressive weakening of their muscles, heart and central nervous system. Both Chuckie and Michael eventually lost control of their eye muscles, for instance.
Falk and colleagues analyzed data from four subjects affected with Leigh syndrome who did not have a specific genetic diagnosis: the Barnett boys and two unrelated patients from Ashkenazi families now living with Leigh syndrome who are followed by the CHOP Mitochondrial Medicine Frontier Program. The team identified a common causative mutation in the nuclear gene USMG5, a gene not previously associated with any human disease. USMG5 encodes a protein component of complex V, the molecular motor within the mitochondrial energy system that directly generates ATP, each cell's chemical energy currency.
The change in USMG5 is a founder mutation, one that originated by chance, most likely centuries ago in an unidentified individual from an Ashkenazi Jewish population, possibly in Eastern Europe. The mutation causes an autosomal recessive disease, so someone can carry the mutation in one of their pair of USMG5 genes without having disease symptoms. However, if both parents are mutation carriers--as is true of Marsha and Allen--each child has a 25 percent chance of inheriting the mutation on both copies of their gene, and being affected with Leigh syndrome. The youngest Barnett son, now 40 years old, does not have Leigh syndrome.
Nearly 30 years ago Marsha and Allen Barnett established a foundation to support research in mitochondrial disease, which subsequently supported the recruitment to CHOP of mitochondrial medicine pioneer Douglas C. Wallace, PhD, where he established the Center for Mitochondrial and Epigenomic Medicine in 2010. Wallace holds the Michael and Charles Barnett Endowed Chair in Pediatric Mitochondrial Medicine and Metabolic Disease.
Insights from the current research have implications for preventive medicine and genetic counseling, says Falk. The USMG5 mutation should be added to the list of mutations tested for at the time of prenatal genetic carrier screening in prospective Ashkenazi Jewish parents. The mutation is relatively common in the Ashkenazi population, where roughly one in 175 individuals are carriers. It should also be added to the list of genes to be evaluated in children with Leigh syndrome.
"What we've learned from these four children recognized to suffer from USMG5 deficiency will enable future children diagnosed with this condition to be very carefully monitored and managed when they face stressors such as fever or anesthesia, to avoid decompensation," said Falk. Decompensation is a rapid medical deterioration that may occur when a patient's system is stressed. In the longer run, Falk and other researchers are working to realize precision medicines for mitochondrial disease. In the future, children known to have this gene disorder may be able to receive treatments targeted to their specific disease.
"This work highlights the importance to families and medicine of continuing to work to solve cases that have never before been fully understood," says Falk. "The current revolution in genomic sequencing methods, combined with highly collaborative research investigations to validate genetic leads, continues to deepen our knowledge of mitochondrial disease, and with it, precision diagnosis, counseling, management, and therapies."

Historian tells new story about England's venerated 'Domesday book'

Nearly a thousand years ago, a famous king created a famous book, later given the title "Domesday" (pronounced "doomsday").

At least that's been the common story: William the Conqueror, 20 years after his 1066 invasion of England from Normandy, ordered a massive survey of his new realm. One year later, he got a book with the results - a record of the nation's wealth and resources, everything from property to sheep to servants.

The "Great Domesday Book," as it was later named, is perhaps the most famous document in English history after the Magna Carta.

The book's origin story, however, had not been thoroughly investigated until University of Illinois history professor Carol Symes took up the task. "What had never been resolved is how this massive text was really created," Symes said, "and in this incredibly narrow timeframe."

Now, after years of research, Symes makes the case in the journal Speculum that the final "Great Domesday Book" came years and perhaps decades later than the 1087 date to which it's attributed, also the year of William's death.

It also was not the orderly bureaucratic enterprise that's often assumed, but instead "enabled hundreds of thousands of individuals and communities to air grievances and to make their own ideas of law and justice a matter of public record," Symes wrote.

"This is documentation of the trauma of conquest. We're watching people pushing back, or at least letting their voices be heard because they're fed up," she said. In one example, the text records townspeople bitterly complaining about the leveling of houses to build a castle.

"We need to rethink what has seemed to be a rather straightforward, top-down royal project, but is revealed to be the tip of a big, monstrous iceberg that involves the agency of many historical actors and often preserves their voices. This helps to tell a very different story about one of the landmark events of England - the Norman conquest and its aftermath - that is not just a story about 'the great man.'"

The universe of the "Domesday Book" is complicated, to say the least. The name is attached to two different bodies of text, "Great Domesday" and "Little Domesday" - the first covering all of the country's shires except three in the southeast, the second covering those three, but in more detail, suggesting it was an earlier draft.

There's also "Exeter Domesday," a collection of 103 booklets that appears to be an even earlier draft of survey results, mostly covering three shires in the southwest.

Curiously, London does not appear in any of these records, which likely is a sign its citizens either ignored the inquest or overwhelmed it with grievances, Symes said. The Exeter collection is just one of many "satellite" documents that have some connection with the survey or book but have received little scholarly attention, Symes said. For many who focus their research on "Great Domesday," the book has been "the sun around which everything else spins."
 Among Symes' contributions is to suggest ways that the different texts relate to each other, since that hasn't been clear. "I think I have figured out the workings behind how this book ("Great Domesday") was made," she said.

Most of Symes' research focused on the Exeter collection and another satellite document, a small fragment of parchment roll, perhaps the oldest in England, from an abbey at Burton-on-Trent in the northwest of the country. In both cases, she examined the original documents.

The Exeter documents provide numerous clues on how "Great Domesday" was assembled, but also serve as a window on the people and the process. A bishop can be seen intervening with the king's advisers when his property is not recorded. Teenage scribes make drinking plans in the marginal notes of manuscripts.

The abbey's parchment fragment, however, is key to Symes' contention that the final book came years and even decades later. She ties its contents to the comings and goings of a man who served at one time as its abbot, who had access to the survey data that went into "Domesday" and may even have been involved in the survey.

"It plugs a huge hole that we had in our evidence. It suggests that the process of creating the thing we call 'Great Domesday' actually took a lot longer than people had thought." Symes said she was attracted to this particular book as part of her interest in medieval manuscripts, especially the complex ways in which they were "mediated" - i.e., written, handled, copied, recopied, added to, edited, interpreted and heard by audiences, all in an age before the printing press. Historians need to take a text's complex mediation into account, she said, even considering the parchment on which it was written, to fully understand and not misinterpret it.

Symes also likes messiness - finding out "how the sausage gets made." She was attracted to Domesday, in part, "because it's a messy document that people pretend is not messy. It's taken to be this pristine, transparent thing when it's not."

One value in the Domesday research, she said, is in "realizing that the people of almost a thousand years ago were real people with real human emotions and needs. We're putting on a different set of glasses to look at these sources, and what we see is all those people who were written out of the record. We're getting to see and hear them again."

The "wonderful irony," Symes said, is that we can do that through one of the most famous books created in the Middle Ages, by a king.